Jizz

Binding of Isaac - Magdalene

rule34

Just me and my little friend, waiting out Isaac.

ladybonersgw

If Hurricane Isaac can't keep me from Titty Tuesday, nothing will. (f)

gonewild

Fuck Isaac! (X-post from /r/pics)

firstworldanarchists

On December 25th, we in our hearts observe the birthday of a great man whose divine and unprecedented life's work changed how we view the world (f)orever. Happy birthday, Lord Sir Isaac Newton ♥

GoneWildPlus

Binding of Isaac: 7 Sins and Mom

rule34

When Isaac finally tells Nicole he has to let go. (DS2)

DeadSpace

Grey Delisle and Jason Isaacs roles.

TheLastAirbender

[Fan Art?] King Isaac, Hobby horse, and angel wiener (semi-NSFW)

bindingofisaac

NOW it feels like Isaac. Hello again, old friend.

bindingofisaac

(SPOILERS) Mega Isaac VS ...

bindingofisaac

So I am pretty good at Isaac/s

bindingofisaac

Hold still Isaac.

bindingofisaac

I found this on the Binding of Isaac rule 34 sub.

MonsterGirl

Something I took quick between doing some Binding of Isaac runs

gaymersgonewild

Fem Null and Isaac

TBoIRule34

Hot Pride on Pride action while Isaac gets bukkaked in the face

TBoIRule34

Sally (Formerly Isaac), Making the Sales.

XChangePill

Tryin' to get back into isaac for Afterbirths release soon so have a quick Little Horn!

TBoIRule34

Greed poses dramatically while Isaac sucks his dong

TBoIRule34

Afterbirth got me wanting to draw Isaac fan art again

bindingofisaac

What a wonderful night to have a curse... [The Binding Of Isaac]

futanari

Daddy and I were playing Isaac today and he got items that i thought made him sooo cute and little!! He has a binky and a big cute bow! (And im the tiny icy familiar! Hehe)

littlespace

Guess i draw something isaac ! Don't worry i take request !

TBoIRule34

We've gone full Deli. There is no more Isaac. There is only Deli now.

TBoIRule34

was bored, didn't know what to draw, I lack patients to do anything amazing, (Also can't think of a good name other then ladies of Isaac or sum shit(this title is stupid))

TBoIRule34

[HC] WIP of my Precious Boy Isaac

FurryArtSchool

Chase Isaacs (@CmIsaacs) photographed by Mark Jenkins

Pecs

Emily Isaacs by Josh Rhodes [OC]

NSFWfashion

Good morning! Three bears streaming Binding of Isaac! twitch.tv/foxboxgamers

gaybears

Edwina Carla Isaacs

CinnamonWomen

Nicole Isaacs has HUGE ones

BustyPetite, 2busty2hide

Body art with Rafael Isaac

LadyBoners

Rafael Isaac Gomez

malemodelsNSFW

KLL Bran the Broken (Isaac Hempstead Wright)

KindaLooksLike

[comic excerpt] Some unlettered art from MONEY SHOT #1 just announced from Vault. Written by Tim Seeley with Sarah Beattie, drawn by Rebekah Isaacs, colored by Kurt Michael Russell (OP), lettered by Crank. I can't wait for people to read this.

comicbooks

Paused binding of Isaac to be here (OC)

RealAhegao

Paused binding of Isaac to be here (OC)

RealAhegao

Gamer boi (OC) I pretty much only play binding of Isaac it's so good

bois

The Lewding of Isaac: The Fly Update

TBoIRule34

Sketch of The Siren (luminescentgoat) [The Binding of Isaac: Repentance]

rule34

I was playing the binding of isaac naked in bed and decided the lighting was too good not to show it off ?

pussy

The Character Select screen if Isaac were a Coomer

TBoIRule34

[oc] Isaac gives Big Horn a tiny smooch (he's trying his best)

TBoIRule34

The Lewding of Isaac: the Repentance compatibility update

TBoIRule34

She gives me a spitty twisty while we watch an Isaac run

gamersgonewild, GamingNSFW_GamerGirls, DirtyGaming

The Lewding of Isaac: The Baby Plum Update

TBoIRule34