Jizz

Hi Guys, this is my down syndrome friend's first time seeing his only friend, his brother, after 2 years of living in a mental asylum. His happiness simply glows from his face!

WangLin

[le] glorious ms paint art my hot sister made. Did I mention she has down syndrome? [9]

circlejerk

Rescued this Saganmese black cat from the pound last April 20th. It has now developed severe dyslexia and down-syndrome. Can you help him, Reddit?

circlejerk

[50/50] Zoe Quinn licking a lollipop | Mussolini's downs syndrome daughter

circlejerk

i overheard this gem from an older lady to her visibly down syndrome sister about her fear of a possible colonoscopy, while sitting in the ER waiting room.

AdviceAnimals

Me after I PHace PHuck an 8 year old with Down syndrome.

PHagville

Indiana banned aborting down syndrome fetus'

ImGoingToHellForThis

Brexit sounds like the punchline to a Downs Syndrome meme to me...

ImGoingToHellForThis

Mikayla Holmgren makes history as first woman with Down syndrome to compete in a Miss USA State Pageant. Think she's DTF?

ImGoingToHellForThis

Hugh Downs Syndrome nsfw

ImGoingToHellForThis